
JOINT HEALTH SUPPORT
Reduce Symptoms of Mild Arthritis
Formulated with our AP-4® Rosa canina rosehip powder and natural vitamin C, SUKOFLEX® helps relieve symptoms of mild arthritis and mild joint pain — supporting mobility and joint comfort as part of your daily routine
— ARTHRITIS
What is Arthritis?
Arthritis is one of the most common causes of joint pain, stiffness, and reduced mobility. It develops from a mix of cartilage wear, joint stress, and chronic low-grade inflammation — understanding what's happening inside the joint is the first step toward lasting comfort.
What Causes Arthritis?
Arthritis develops due to a combination of factors:
Age-related cartilage changes
Joint injuries or overuse
Excess mechanical stress on joints
Inflammation and metabolic factors
For example, joint injuries significantly increase the risk of developing osteoarthritis later in life, especially in weight-bearing joints like the knee.

THE POWER OF ROSEHIP
Three ways rosehip supports your joints
Pain & stiffness relief
Helps reduce joint pain and stiffness, supporting everyday comfort.
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Joint comfort
Supports overall joint comfort, backed by clinical studies (Mahajan et al., 2020; Christensen et al., 2008).
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INFLAMMATION
What's Happening Inside an Inflamed Joint?
Arthritis is not just "wear and tear" — it also involves chronic low-grade inflammation.
Inside the joint:
Inflammatory signals like TNF-α, IL-1β, and IL-6 are released
These activate enzymes that break down cartilage (e.g. MMPs)
Oxidative stress further contributes to joint damage
Over time, this leads to:
Cartilage degradation
Reduced joint function
Increased pain and stiffness
ROSEHIP SCIENCE
Rosehip and joint health
Rosa canina rosehip is one of the most studied plant-based ingredients for joint support.
Clinical and experimental research suggests that rosehip may:
Help reduce joint pain and stiffness
Improve physical function and mobility
Support overall joint comfort
In clinical studies, patients taking rosehip extract experienced significant improvements in pain, stiffness, and function over time (Mahajan et al., 2020).
A meta-analysis of randomized trials also found that rosehip was associated with reduced pain and increased likelihood of symptom improvement compared to placebo (Christensen et al., 2008).


MECHANISM OF ACTION
Why AP-4® Rosa canina Rosehips Works
Our AP-4® Rosa canina rosehips contains a unique combination of bioactive compounds that act on multiple pathways involved in joint health.
1. Anti-inflammatory activity
Rosehips have been shown to reduce inflammatory mediators such as TNF-α, IL-6, and prostaglandins, and inhibit key enzymes like COX-1 and COX-2 involved in inflammation. (Wenzig et al., 2008)
2. Cartilage protection
Rosehip and its active compounds reduce expression of cartilage-degrading enzymes (MMPs) and support a healthier balance between cartilage breakdown and repair. (Schwager et al., 2011)
3. Antioxidant support
AP-4® Rosa canina rosehips are rich in polyphenols, vitamin C, and carotenoids — these help reduce oxidative stress, which contributes to joint degeneration. (Wenzig et al., 2008)









